Although most children with coronavirus disease 2019 (COVID-19) infection present with mild symptoms, a few pediatric patients develop severe neurological manifestations.Herein, we describe the case of Merchandise a pediatric patient who presented with rapidly progressive diffuse and fatal cerebral edema associated with COVID-19.A previously health
Abstract Background Temozolomide (TMZ) is the most commonly used chemotherapeutic agent used to treat glioblastoma (GBM), which causes significant DNA damage to highly proliferative cells.Our observations have added to accumulating evidence that TMZ induces stress-responsive cellular programs known to promote cell survival, including autophagy.As s
Fuzzy c-means clustering (FCM) has proved highly successful in the manipulation and analysis of image information, such as image segmentation.However, the effectiveness of FCM-based technique is limited by its poor robustness to noise and edge-preserving during the segmentation process.To tackle these problems, a new objective function of FCM is de